Neuropathy Digest Volume II. Selections include: POTS and reduced epidermal nerve fiber density (ENFD), and muscle cramps in diabetes.

Christopher Gibbons and colleagues, from Boston, MA, reported on their studies in 14 patients with Postural Tachycardia Syndrome (POTS). They found that 7 of the 14 had neuropathic POTS, with decreased intraepidermal nerve fiber (IENF) density, but with no difference in quantitative sensory testing. Symptoms profile were similar in both neuropathic and non-neuropathic POTS. Identification of small fiber neuropathy may have therapeutic implications in patients with POTS.