Research Finds Nerve Damage in Patients with Fibromyalgia
Objective skin test for small fiber neuropathy
NEW YORK, Dec. 16, 2014 /PRNewswire/ — Therapath, LLC (www.therapath.com), a leader in neuropathology laboratory services, reports that new findings have revealed that patients diagnosed with fibromyalgia may also have a diagnosable small fiber neuropathy. Recently, several studies have examined fibromyalgia patients for small fiber neuropathy using a skin biopsy test to determine Epidermal Nerve Fiber Density (ENFD). The studies reported a decrease in ENFD in a subset of patients with fibromyalgia (Oaklander et al., Pain 2013; Caro & Winter, Arthritis Rheumatology 2014; Giannoccaro et al., Muscle Nerve 2014). These studies conclude that ENFD testing should be considered in the diagnostic work-up of fibromyalgia to search for small fiber neuropathy.
www.therapath.com/rheumatology
Patients diagnosed with small fiber neuropathy exhibit similar symptoms to those with fibromyalgia, including:
- Chronic pain
- Increased sensitivity to pressure and touch
- Numbness and tingling
Epidermal Nerve Fiber Density (ENFD) is an objective measure of the small nerve fibers. To perform the test, a doctor performs a biopsy in the office to obtain a small piece of skin. That skin sample is then sent to a neuropathology laboratory for analysis. Patients with small fiber neuropathy exhibit a significant reduction in the ENFD. www.therapath.com/enfd
About Therapath Neuropathology:
Therapath Neuropathology, founded in 2004, is a College of American Pathology accredited (CAP) and CLIA licensed specialized laboratory. The medical team are board certified in neuropathology, academically trained and extensively published. Therapath’s focus is on research and development in the testing services for muscle biopsy, nerve biopsy with teased fiber analysis, ocular (including optic neuritis), skin epidermal nerve fiber density, sweat gland nerve fiber density, skin biopsy for CADASIL and other storage disorders as well as brain/spinal cord specimens. Therapath serves hospitals, private practitioners, reference laboratories, the pharmaceutical industry, and researchers throughout the United States and internationally.
Contact:
Therapath Neuropathology
Geoff Whitehouse, 800-681-4338
gwhitehouse@therapath.com
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Research Finds Nerve Damage in Patients with Fibromyalgia
Objective skin test for small fiber neuropathy
NEW YORK, Dec. 16, 2014 /PRNewswire/ — Therapath, LLC (www.therapath.com), a leader in neuropathology laboratory services, reports that new findings have revealed that patients diagnosed with fibromyalgia may also have a diagnosable small fiber neuropathy. Recently, several studies have examined fibromyalgia patients for small fiber neuropathy using a skin biopsy test to determine Epidermal Nerve Fiber Density (ENFD). The studies reported a decrease in ENFD in a subset of patients with fibromyalgia (Oaklander et al., Pain 2013; Caro & Winter, Arthritis Rheumatology 2014; Giannoccaro et al., Muscle Nerve 2014). These studies conclude that ENFD testing should be considered in the diagnostic work-up of fibromyalgia to search for small fiber neuropathy.
www.therapath.com/rheumatology
Patients diagnosed with small fiber neuropathy exhibit similar symptoms to those with fibromyalgia, including:
- Chronic pain
- Increased sensitivity to pressure and touch
- Numbness and tingling
Epidermal Nerve Fiber Density (ENFD) is an objective measure of the small nerve fibers. To perform the test, a doctor performs a biopsy in the office to obtain a small piece of skin. That skin sample is then sent to a neuropathology laboratory for analysis. Patients with small fiber neuropathy exhibit a significant reduction in the ENFD. www.therapath.com/enfd
About Therapath Neuropathology:
Therapath Neuropathology, founded in 2004, is a College of American Pathology accredited (CAP) and CLIA licensed specialized laboratory. The medical team are board certified in neuropathology, academically trained and extensively published. Therapath’s focus is on research and development in the testing services for muscle biopsy, nerve biopsy with teased fiber analysis, ocular (including optic neuritis), skin epidermal nerve fiber density, sweat gland nerve fiber density, skin biopsy for CADASIL and other storage disorders as well as brain/spinal cord specimens. Therapath serves hospitals, private practitioners, reference laboratories, the pharmaceutical industry, and researchers throughout the United States and internationally.
Contact:
Therapath Neuropathology
Geoff Whitehouse, 800-681-4338
gwhitehouse@therapath.com
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Epidermal Nerve Fiber Density Test – Biopsy Sites
therapath2022-09-05T19:02:43-05:00
Therapath has established five standard biopsy sites for Epidermal Nerve Fiber Density (ENFD) and Sweat Gland Nerve Fiber Density (SGNFD). [Read More]
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therapath2022-09-05T19:01:46-05:00
De Greef et al. studied 921 patients with confirmed small fiber neuropathy in order to investigate the prevalence of associated conditions in SFN patients. [Read More]
Abstract: Idiopathic Small Fiber Neuropathy in Children
therapath2022-09-05T17:30:24-05:00
Balushi, Kim, Krause, and Kafie looked at idiopathic small fiber neuropathy findings in children who had small fiber neuropathy confirmed by history, clinical exam, and low intraepidermal nerve fiber density. [Read More]
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therapath2022-09-05T17:45:25-05:00
Thaisetthawatkul, Fernandes, and Herrmann looked at the connection between prediabetes and small fiber neuropathy. [Read More]