Systematic Review Presents Current Understanding of Small Fiber Neuropathy
The review, published in the May 2016 issue of Muscle & Nerve, provides a comprehensive evaluation of Small Fiber Neuropathy (SFN) research.
Few systematic reviews have addressed the emerging topic of SFN over the last decade. In this review we present an up-to date understanding of SFN by addressing epidemiology,etiology, clinical presentation, diagnosis, pathophysiology, treatment, and outcome.
The authors compare several diagnostic methods for SFN and note that epidermal nerve fiber density (ENFD) through punch biopsy is sensitive, reliable, and efficient.1
In discussing etiology, the review highlights the importance of ENFD analysis for fibromyalgia patients.
Identifying SFN in fibromyalgia patients not only provides a specific diagnosis but also increases treatment options.
The review concludes that SFN patients require a “pragmatic workup…to optimize treatment”.1 The full article is available in Muscle & Nerve.
- Chan A, Wilder-Smith E. Small fiber neuropathy: Getting bigger! Muscle Nerve. 2016;53(5):671-682. [PubMed]
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Epidermal Nerve Fiber Density Test – Biopsy Sites
therapath2022-09-05T19:02:43-05:00
Therapath has established five standard biopsy sites for Epidermal Nerve Fiber Density (ENFD) and Sweat Gland Nerve Fiber Density (SGNFD). [Read More]
Abstract: Associated Conditions in Small Fiber Neuropathy
therapath2022-09-05T19:01:46-05:00
De Greef et al. studied 921 patients with confirmed small fiber neuropathy in order to investigate the prevalence of associated conditions in SFN patients. [Read More]
Abstract: Idiopathic Small Fiber Neuropathy in Children
therapath2022-09-05T17:30:24-05:00
Balushi, Kim, Krause, and Kafie looked at idiopathic small fiber neuropathy findings in children who had small fiber neuropathy confirmed by history, clinical exam, and low intraepidermal nerve fiber density. [Read More]
Abstract: Prediabetes and Small Fiber Neuropathy
therapath2022-09-05T17:45:25-05:00
Thaisetthawatkul, Fernandes, and Herrmann looked at the connection between prediabetes and small fiber neuropathy. [Read More]
Systematic Review Presents Current Understanding of Small Fiber Neuropathy
The review, published in the May 2016 issue of Muscle & Nerve, provides a comprehensive evaluation of Small Fiber Neuropathy (SFN) research.
Few systematic reviews have addressed the emerging topic of SFN over the last decade. In this review we present an up-to date understanding of SFN by addressing epidemiology,etiology, clinical presentation, diagnosis, pathophysiology, treatment, and outcome.
The authors compare several diagnostic methods for SFN and note that epidermal nerve fiber density (ENFD) through punch biopsy is sensitive, reliable, and efficient.1
In discussing etiology, the review highlights the importance of ENFD analysis for fibromyalgia patients.
Identifying SFN in fibromyalgia patients not only provides a specific diagnosis but also increases treatment options.
The review concludes that SFN patients require a “pragmatic workup…to optimize treatment”.1 The full article is available in Muscle & Nerve.
- Chan A, Wilder-Smith E. Small fiber neuropathy: Getting bigger! Muscle Nerve. 2016;53(5):671-682. [PubMed]
Related Articles
Epidermal Nerve Fiber Density Test – Biopsy Sites
therapath2022-09-05T19:02:43-05:00
Therapath has established five standard biopsy sites for Epidermal Nerve Fiber Density (ENFD) and Sweat Gland Nerve Fiber Density (SGNFD). [Read More]
Abstract: Associated Conditions in Small Fiber Neuropathy
therapath2022-09-05T19:01:46-05:00
De Greef et al. studied 921 patients with confirmed small fiber neuropathy in order to investigate the prevalence of associated conditions in SFN patients. [Read More]
Abstract: Idiopathic Small Fiber Neuropathy in Children
therapath2022-09-05T17:30:24-05:00
Balushi, Kim, Krause, and Kafie looked at idiopathic small fiber neuropathy findings in children who had small fiber neuropathy confirmed by history, clinical exam, and low intraepidermal nerve fiber density. [Read More]
Abstract: Prediabetes and Small Fiber Neuropathy
therapath2022-09-05T17:45:25-05:00
Thaisetthawatkul, Fernandes, and Herrmann looked at the connection between prediabetes and small fiber neuropathy. [Read More]
